Octopunk provides a familiar but enhanced issues and pull request UI.
An outline is provided on the left drawer of both issues and pull request pages. This allows you to quickly jump to interesting events within the issue or pull.
Pull requests support the familiar code review flows GitHub has pioneered including submitting reviews, resolving comment threads, and merging the pull requests.
The diff viewer supports filtering by commit, supporting commit-wise reviews.
The issues pages support sub-issues and issue relationships.